Mechanisms of Disease: Is Mitochondrial Function Altered in Heart Failure?
نویسندگان
چکیده
منابع مشابه
Altered contractile function in heart failure.
The syndrome of congestive heart failure (CHF) is an entity of ever increasing clinical significance. CHF is characterized by a steady decrease in cardiac pump function which is eventually lethal. The mechanisms that underlie the decline in cardiac function are incompletely understood. End-stage CHF often involves the general loss of functional myocytes, a hyperplasia of the extracellular matri...
متن کاملIs there any difference between Vitamin D deficiency among heart failure and Non-heart failure elderly with cardiovascular disease?
Vitamin D deficiency is common among the elderly with and without heart failure (HF). This study was designed to identify the degree of vitamin D deficiency among HF and Non- HF elderly with cardiovascular disease. In this study, fifty hospitalized elderly patients with HF (26 women and 24 men, age range 60-90 years) and fifty elderly without HF were randomly selected. The level of serum 25-hyd...
متن کاملMechanisms of altered Ca²⁺ handling in heart failure.
Ca²⁺ plays a crucial role in connecting membrane excitability with contraction in myocardium. The hallmark features of heart failure are mechanical dysfunction and arrhythmias; defective intracellular Ca²⁺ homeostasis is a central cause of contractile dysfunction and arrhythmias in failing myocardium. Defective Ca²⁺ homeostasis in heart failure can result from pathological alteration in the exp...
متن کاملMechanisms of Altered Ca2+ Handling in Heart Failure
Among the many causes of myocardial injury that can lead to congestive heart failure (CHF), myocardial infarction (MI) is the most common in the developed world. The hallmark features of heart failure include reduced contractile function manifested as blunted, slowed, dysynchronous contraction and impaired relaxation. The physiological positive force–frequency relationship and increased myocard...
متن کاملinterpersonal function of language in subtitling
translation as a comunicative process is always said to be associated with various aspects of meaning loss or gain. subtitling as a mode of translating, due to special discoursal and textual conditions imposed upon it, is believed to be an obvious case of this loss or gain. presenting the spoken sound track of a film in writing and synchronizing the perception of this text by the viewers with...
15 صفحه اولذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Methodist DeBakey Cardiovascular Journal
سال: 2013
ISSN: 1947-6094
DOI: 10.14797/mdcj-9-1-44